Yin and yang symbol using arabian horses

Д¬A is found in Arabians and partbred Arabian horses but it has also been reported in the Gotland pony and the Oldenburg Warmblood horse. An inherited polymorphism is assumed to be responsible for the changes in the metabolic activity of the Purkinje neurons. In conclusion, morphometric MRI and genetic analysis could be helpful to support the diagnosis of CA in vivo.Д¬erebellar abiotrophy (CA) is a neurological disease characterized by intrinsic spontaneous degeneration of premature neuronal cells. Using a cut off value of 11.0% for relative cerebellar CSF space, the parameter differentiated between CA-affected horses and controls with a sensitivity of 100% and a specificity of 93.3%. The relative cerebellar CSF space was larger in affected horses ( P = 0.0017). It was demonstrated that in MR morphometric analyses, CA affected horses displayed a relatively smaller cerebellum compared to the entire brain mass than control animals ( P = 0.0088). On MR images morphometric analysis of the relative cerebellar size and relative cerebellar cerebrospinal fluid (CSF) space were compared to control images of 15 unaffected horses. ResultsД¬A was diagnosed pathohistologically in the five affected horses (2 months - 3 years) supported by clinical signs, necropsy, and genetic testing which confirmed the TOE1:g.2171G>A SNP genotype A/A in all CA-affected horses. Therefore, the objective of this study was to perform MR morphometric analysis and genetic testing in four CA-affected Arabian horses and one German Riding Pony with purebred Arabian bloodlines in the third generation.

Due to the hereditary nature of the disease, genetic testing can support the diagnosis of CA. The role of MR morphometry in this regard is currently unknown. However, as yet MR imaging has only been described in one equine CA case. The specific role of magnetic resonance imaging (MRI) to support clinical diagnosis has been discussed. Cerebellar abiotrophy (CA) is a rare but significant disease in Arabian horses caused by progressive death of the Purkinje cells resulting in cerebellar ataxia characterized by a typical head tremor, jerky head movements and lack of menace response.

Yin and yang symbol using arabian horses